Effect of Maternal Zinc Supplementation on Birth Weight and Neonatus Zinc Status
Sri Sumarmi*, Sri Adiningsih*, L.Y. Hendrati** and Diffah Hanim***
*Departemen Gizi Kesehatan FKM Unair Surabaya
**Departemen Epidemilogi FKM Unair Surabaya
***Laboratorium Gizi FK UNS Surakarta
*Departemen Gizi Kesehatan FKM Unair Surabaya
**Departemen Epidemilogi FKM Unair Surabaya
***Laboratorium Gizi FK UNS Surakarta
Anemia among pregnant women is still very prevalent and hard to controlled. Besides, zinc deficiency is also found among pregnant women and interaction between iron and zinc is interesting to investigate.
This study was conducted to investigate effect of zinc supplementation to maternal zinc status, neonatus zinc status and birth weight. A quasy experimental study by pre test-post test control group design was conducted in cachtment area of 3 Health Centers in Sukoharjo District, Central Java.
Method : Screening was carried out to 57 pregnant women to determine experimental and control group. Using concentration of serum zinc 70 m g/dL as cut off point. 34 pregnant women recruited as experimental group and supplemented with + 30 mg Zn as zinc sulphate daily during third trimester of pregnancy and Fe sulphate (60mg iron daily), seventeen pregnant women recruited as control group supplemented with Fe sulphate (60mg iron daily). Maternal zinc status and hemoglobin level before and after intervention were analyzed to investigate predictor of birth weight and neonatus zinc status (zinc concentration of umbilicus cord). The differences of maternal zinc status in last trimester, Hb level, umbilicus zinc and birth weigth among responden in experimental group and control group were analized using ANOVA. To study the effect of zinc supplementation to birth weigth data were analyzed using ANA CO VA with Hb level in last trimestrer as covariate.
Result : Maternal serum zinc level in last trimester (p=O.0l), Hb level in last trimester (p = 0.44), umbilicus zinc level (p=0.00) were significantly different between experimental and control group, but not for birth weight of new born (p =0, 08). With Hb level in last trimester as covariate, there was a sign d of bfrth weight among experimen tal and control group(p = 0.0/).
Conclusion : Zinc supplementation to pregnant women improve zinc level, hemoglobin and umbilical zinc level. The zinc levelá is still lover than normal value.
This study was conducted to investigate effect of zinc supplementation to maternal zinc status, neonatus zinc status and birth weight. A quasy experimental study by pre test-post test control group design was conducted in cachtment area of 3 Health Centers in Sukoharjo District, Central Java.
Method : Screening was carried out to 57 pregnant women to determine experimental and control group. Using concentration of serum zinc 70 m g/dL as cut off point. 34 pregnant women recruited as experimental group and supplemented with + 30 mg Zn as zinc sulphate daily during third trimester of pregnancy and Fe sulphate (60mg iron daily), seventeen pregnant women recruited as control group supplemented with Fe sulphate (60mg iron daily). Maternal zinc status and hemoglobin level before and after intervention were analyzed to investigate predictor of birth weight and neonatus zinc status (zinc concentration of umbilicus cord). The differences of maternal zinc status in last trimester, Hb level, umbilicus zinc and birth weigth among responden in experimental group and control group were analized using ANOVA. To study the effect of zinc supplementation to birth weigth data were analyzed using ANA CO VA with Hb level in last trimestrer as covariate.
Result : Maternal serum zinc level in last trimester (p=O.0l), Hb level in last trimester (p = 0.44), umbilicus zinc level (p=0.00) were significantly different between experimental and control group, but not for birth weight of new born (p =0, 08). With Hb level in last trimester as covariate, there was a sign d of bfrth weight among experimen tal and control group(p = 0.0/).
Conclusion : Zinc supplementation to pregnant women improve zinc level, hemoglobin and umbilical zinc level. The zinc levelá is still lover than normal value.
Key words : pregnancy, zinc deficiency, maternal zinc status, birth weight
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Research financial supported by : National Health Research and Development Institute, MoH (Badan Litbang Kes Depkes RI) (2001).
